Stool-Based Screening Tests for Colorectal Cancer
- PMID: 36800187
- PMCID: PMC10386850
- DOI: 10.1001/jama.2023.0547
Stool-Based Screening Tests for Colorectal Cancer
Plain language summary
A 56-year-old man with no significant medical history has declined screening colonoscopy at previous physician visits but wants to undergo a less invasive test because his father died of colorectal cancer at age 80. What would you do next?
Conflict of interest statement
Dr. Carethers reports grants from the National Cancer Institute and funds from the University of Michigan during the conduct of the study. Dr. Carethers reports personal fees from Avantor, Inc., provided consultancy to Geneoscopy, Inc., and being a Board member for the American Gastroenterology Association and on the Advisory Board for the National Institute for Diabetes and Digestive and Kidney Diseases outside of the submitted work.
Similar articles
-
Early Detection of Colorectal Cancer: a Multi-Center Pre-Clinical Case Cohort Study for Validation of a Combined DNA Stool Test.Clin Lab. 2018 Oct 1;64(10):1719-1730. doi: 10.7754/Clin.Lab.2018.180521. Clin Lab. 2018. PMID: 30336540
-
Interventions to Increase Follow-Up of Abnormal Stool-Based Colorectal Cancer Screening Tests in Safety Net Settings: A Systematic Review.Gastroenterology. 2024 Oct;167(5):826-833.e3. doi: 10.1053/j.gastro.2024.08.002. Gastroenterology. 2024. PMID: 39306373 No abstract available.
-
KRAS mutations and M2PK upregulation in stool samples from individuals with positive fecal occult blood tests screened for colorectal cancer.Tumori. 2014 Mar-Apr;100(2):122-7. doi: 10.1177/030089161410000202. Tumori. 2014. PMID: 24852854
-
Faecal Occult Blood Point-of-Care Tests.J Gastrointest Cancer. 2018 Dec;49(4):402-405. doi: 10.1007/s12029-018-0169-1. J Gastrointest Cancer. 2018. PMID: 30232694 Free PMC article. Review.
-
A Clinician's Guide to Fecal Occult Blood Testing for Colorectal Cancer.South Med J. 2016 Apr;109(4):248-55. doi: 10.14423/SMJ.0000000000000449. South Med J. 2016. PMID: 27043809 Review.
Cited by
-
Genomic-Based Early Detection Screening: A Literature Review of Prospective Trials and Emerging Strategies for Gastrointestinal Cancers.Cureus. 2024 Sep 7;16(9):e68881. doi: 10.7759/cureus.68881. eCollection 2024 Sep. Cureus. 2024. PMID: 39246640 Free PMC article. Review.
-
THE JEREMIAH METZGER LECTURE: ENVIRONMENTAL INFLUENCES ON COLORECTAL CANCER.Trans Am Clin Climatol Assoc. 2024;134:181-199. Trans Am Clin Climatol Assoc. 2024. PMID: 39135583 Free PMC article.
-
Unveiling Colorectal Cancer Biomarkers: Harnessing Biosensor Technology for Volatile Organic Compound Detection.Sensors (Basel). 2024 Jul 20;24(14):4712. doi: 10.3390/s24144712. Sensors (Basel). 2024. PMID: 39066110 Free PMC article. Review.
-
Commentary: Liquid Biopsy for Average-Risk Colorectal Cancer Screening.Clin Gastroenterol Hepatol. 2024 Jun;22(6):1160-1164.e1. doi: 10.1016/j.cgh.2024.01.034. Epub 2024 Mar 26. Clin Gastroenterol Hepatol. 2024. PMID: 38552672 Free PMC article. No abstract available.
-
Improving Noninvasive Colorectal Cancer Screening.N Engl J Med. 2024 Mar 14;390(11):1045-1046. doi: 10.1056/NEJMe2400366. N Engl J Med. 2024. PMID: 38477992 Free PMC article. No abstract available.
References
-
- US Preventive Services Task Force, Davidson KW, Barry MJ, Mangione CM, Cabana M, Caughey AB, Davis EM, Donahue KE, Doubeni CA, Krist AH, Kubik M, Li L, Ogedegbe G, Owens DK, Pbert L, Silverstein M, Stevermer J, Tseng CW, Wong JB. Screening for Colorectal Cancer: US Preventive Services Task Force Recommendation Statement. JAMA. 2021. May 18;325(19):1965–1977. doi: 10.1001/jama.2021.6238. Erratum in: JAMA. 2021 Aug 24;326(8):773. - DOI - PubMed
-
- Carethers JM. Fecal DNA testing for colorectal cancer screening. Annu Rev Med 2020;71:59–69. - PubMed
-
- Robertson DJ, Lee JK, Boland CR, Dominitz JA, Giardiello FM, Johnson DA, Kaltenbach T, Lieberman D, Levin TR, Rex DK. Recommendations on fecal immunochemical testing to screen for colorectal neoplasia: a consensus statement by the US Multi-Society Task Force on Colorectal Cancer. Am J Gastroenterol 2017;112:37–53. - PubMed
-
- Imperiale TF, Ransohoff DF, Istzkowitz SH, Levin TR, Lavin P, Lidgard GP, Ahlquist DA, Berger BM. Multitarget stool DNA testing for colorectal-cancer screening. N Eng J Med 2014;370:1287–1297. - PubMed
Publication types
MeSH terms
Grants and funding
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical
