Mesencephalic locomotor region stimulation-cuneiform or pedunculopontine?

Cell Rep Med. 2023 Feb 21;4(2):100948. doi: 10.1016/j.xcrm.2023.100948.


Roussel et al.1 provide new insight into mecencephalic locomotor region (MLR) stimulation to treat spinal cord injury in mice. Previously, it was unclear which part of the MLR to target. Now, evidence converges on cuneiform nucleus activation.

MeSH terms

  • Animals
  • Locomotion* / physiology
  • Mesencephalon* / physiology
  • Mice