Minimal-change nephrotic syndrome in adults treated with alternate-day steroids

Nephron. 1987;47(3):209-10. doi: 10.1159/000184494.

Abstract

Fifty-eight previously untreated adults with minimal-change nephrotic syndrome (MCNS), who had a mean follow-up period of 35.8 months, were studied with regard to their response to alternate-day steroid therapy. The nephrotic syndrome in 54 patients (93%) remitted by 12 weeks and patients continued to be in remission at 16 weeks. Of the 54 patients, 8 (14.8%) had frequent relapses and 9 (16.6%) had infrequent relapses. No serious complications as a result of steroid therapy were encountered.

MeSH terms

  • Adolescent
  • Adult
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Nephrosis, Lipoid / drug therapy*
  • Prednisolone / administration & dosage*
  • Retrospective Studies

Substances

  • Prednisolone