HLA antigens in narcolepsy

Neurology. 1987 Dec;37(12):1858-60. doi: 10.1212/wnl.37.12.1858.

Abstract

Eighteen black patients with narcolepsy underwent human leukocyte antigen (HLA) typing. Eleven of the 18 had cataplexy. Twelve patients (66.6%) had HLA-DR2; 7 patients with cataplexy had DR2. All patients had DQw1. In contrast to white and Japanese patients studied to date, not all black narcoleptics have DR2.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Aged
  • Black People
  • Female
  • HLA Antigens / analysis*
  • HLA-DQ Antigens / analysis
  • HLA-DR Antigens / analysis
  • Humans
  • Male
  • Middle Aged
  • Narcolepsy / immunology*

Substances

  • HLA Antigens
  • HLA-DQ Antigens
  • HLA-DR Antigens