Avascular Peripheral Retina in Infants

Turk J Ophthalmol. 2023 Feb 24;53(1):44-57. doi: 10.4274/tjo.galenos.2022.76436.


Avascular peripheral retina in an infant is a common characteristic of numerous pediatric retinal vascular disorders and often presents a diagnostic challenge to the clinician. In this review, key features of each disease in the differential diagnosis, from retinopathy of prematurity, familial exudative vitreoretinopathy, Coats disease, incontinentia pigmenti, Norrie disease, and persistent fetal vasculature, to other rare hematologic conditions and telomere disorders, will be discussed by expert ophthalmologists in the field.

Keywords: Avascular retina; Coats disease; Norrie disease; familial exudative vitreoretinopathy; incontinentia pigmenti; persistent fetal vasculature; retinopathy of prematurity.

Publication types

  • Review

MeSH terms

  • Child
  • Diagnosis, Differential
  • Humans
  • Infant
  • Infant, Newborn
  • Regional Blood Flow*
  • Retina* / abnormalities
  • Retina* / anatomy & histology
  • Retinal Diseases* / congenital
  • Retinal Diseases* / diagnosis
  • Retinal Diseases* / pathology
  • Retinal Vessels* / abnormalities
  • Retinal Vessels* / pathology