Sphenoid Bone Dysplasia: A Rare Cause of Compressive Optic Neuropathy Mimicking Glaucoma

Turk J Ophthalmol. 2023 Feb 24;53(1):70-73. doi: 10.4274/tjo.galenos.2022.37605.


Fibrous dysplasia is a benign, rare bone disease in which bone is replaced by fibro-osseous tissue to varying degrees. It can present differently depending on the amount of compression caused by the fibro-osseous tissue. Patients are usually asymptomatic, but symptoms related to cranial nerve compression may occur. In this case report, we describe a 45-year-old woman with sphenoid bone dysplasia which compressed the optic nerve and caused unilateral optic disc cupping that mimicked glaucoma. Our case highlights the importance of including compressive etiologies associated with optic disc cupping in the differential diagnosis of glaucoma.

Keywords: Compressive optic neuropathy; glaucoma; sphenoid bone dysplasia.

Publication types

  • Case Reports

MeSH terms

  • Bone Diseases, Developmental*
  • Female
  • Glaucoma* / diagnosis
  • Glaucoma* / etiology
  • Humans
  • Middle Aged
  • Optic Disk*
  • Optic Nerve
  • Optic Nerve Diseases* / diagnosis
  • Optic Nerve Diseases* / etiology
  • Rare Diseases