Object exploration in staggerer mutant mice

Physiol Behav. 1987;41(2):115-7. doi: 10.1016/0031-9384(87)90139-9.

Abstract

Staggerer mutant mice, which lose Purkinje and granule cells in the cerebellum, were found to explore for a longer period of time than normal mice a novel object placed in a familiar environment. There was no difference between the two groups in terms of general motor activity. These results are discussed in regard to a role for the cerebellum in behavioral inhibition and emotion.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Cerebellum / physiology
  • Exploratory Behavior*
  • Mice
  • Mice, Neurologic Mutants / physiology*
  • Motor Activity
  • Time Factors