Susceptibility-Weighted Imaging Reveals Subcortical Iron Deposition in PLA2G6-associated Neurodegeneration: The "Double Cortex Sign"

Mov Disord. 2023 May;38(5):904-906. doi: 10.1002/mds.29364. Epub 2023 Feb 28.

Benjamin Roeben^{1

2}, Lena Zeltner^{1

3}, Gisela E Hagberg^{4

5}, Klaus Scheffler^{4

5}, Ludger Schöls^{1

2

3}, Benjamin Bender⁶

¹ Department of Neurodegenerative Diseases, Hertie-Institute for Clinical Brain Research, University of Tübingen, Tübingen, Germany.
² German Research Center for Neurodegenerative Diseases (DZNE), University of Tübingen, Tübingen, Germany.
³ Center of Rare Diseases (ZSE), University of Tübingen, Tübingen, Germany.
⁴ High Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Tübingen, Germany.
⁵ Biomedical Magnetic Resonance, Eberhard Karl's University, Tübingen and University Hospital, Tübingen, Germany.
⁶ Department of Diagnostic and Interventional Neuroradiology, University of Tübingen, Tübingen, Germany.

No abstract available

Keywords: NBIA; PLA2G6; PLAN; QSM; SWI; neurodegeneration with brain iron accumulation.

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