ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data

STAR Protoc. 2023 Mar 17;4(1):102069. doi: 10.1016/j.xpro.2023.102069. Epub 2023 Jan 25.

Abstract

Understanding cellular metabolism is important across biotechnology and biomedical research and has critical implications in a broad range of normal and pathological conditions. Here, we introduce the user-friendly web-based platform ImmCellFie, which allows the comprehensive analysis of metabolic functions inferred from transcriptomic or proteomic data. We explain how to set up a run using publicly available omics data and how to visualize the results. The ImmCellFie algorithm pushes beyond conventional statistical enrichment and incorporates complex biological mechanisms to quantify cell activity. For complete details on the use and execution of this protocol, please refer to Richelle et al. (2021).1.

Keywords: Bioinformatics; Genomics; Metabolism; Systems Biology.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Computational Biology* / methods
  • Internet
  • Proteomics* / methods