New insights into the mechanisms of anandamide-induced airway dilation placing its degradation enzyme, FAAH center stage. Commentary on: Simon A, von Einem T, Seidinger A, Matthey M, Bindila L, Wenzel D (2022) The endocannabinoid anandamide is an airway relaxant in health and disease. Nat Commun 13:6941

Pflugers Arch. 2023 May;475(5):557-559. doi: 10.1007/s00424-023-02802-2. Epub 2023 Mar 1.
No abstract available

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Amidohydrolases / metabolism
  • Arachidonic Acids* / metabolism
  • Arachidonic Acids* / pharmacology
  • Dilatation
  • Endocannabinoids* / metabolism
  • Enzyme Inhibitors / pharmacology
  • Polyunsaturated Alkamides / metabolism
  • Polyunsaturated Alkamides / pharmacology

Substances

  • anandamide
  • Endocannabinoids
  • Arachidonic Acids
  • Polyunsaturated Alkamides
  • Enzyme Inhibitors
  • Amidohydrolases