[Research progress of medication treatment of pediatric noninfectious uveitis]

Zhonghua Yan Ke Za Zhi. 2023 Mar 11;59(3):231-236. doi: 10.3760/cma.j.cn112142-20220703-00324.
[Article in Chinese]

Abstract

Pediatric uveitis accounts for 5% to 10% of all uveitis, most of which are noninfectious. Most cases have an insidious onset and are accompanied by many complications, which may lead to poor prognosis and intractable treatment. At present, traditional drugs that are commonly employed to treat pediatric noninfectious uveitis include local and systemic corticosteroids, methotrexate and other immunosuppressants. In recent years, the application of various biological agents has provided new means for the treatment of this kind of disease. This article reviews the progress of medication treatment of pediatric noninfectious uveitis.

儿童葡萄膜炎约占所有葡萄膜炎的5%~10%,多为非感染性,通常起病隐匿,可能造成诸多并发症,预后欠佳,治疗棘手。针对儿童非感染性葡萄膜炎,目前传统常用药物有眼局部及全身应用糖皮质激素、甲氨蝶呤等免疫抑制剂。近年来多种生物制剂的应用为该类疾病的治疗提供了新的手段。本文就儿童非感染性葡萄膜炎的药物治疗进展进行综述。.

Publication types

  • Review
  • English Abstract

MeSH terms

  • Child
  • Humans
  • Immunosuppressive Agents*
  • Uveitis*

Substances

  • Immunosuppressive Agents