Inflammatory and senescence-associated mediators affect the persistence of humoral response to COVID-19 mRNA vaccination in transfusion-dependent beta-thalassemic patients

Affiliations

• ¹ Oncoematologia e Officina Farmaceutica, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
• ² Dipartimento della Donna, del Bambino e di Chirurgia Generale e Specialistica, Università, degli Studi della Campania "Luigi Vanvitelli", Naples, Italy.
• ³ Center for Microcythemia, Congenital Anemia, and Iron Dysmetabolism, Galliera Hospital, Genoa, Italy.
• ⁴ B-Cell Laboratory, Immunology Research Area, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
• ⁵ ForAnemia Foundation, Genoa, Italy.
• ⁶ Day Hospital della Talassemia e delle Emoglobinopatie, Dipartimento di Medicina, Azienda Ospedaliero-Universitaria S. Anna, Cona, Italy.
• ⁷ SC Microcitemie e anemie rare, Ospedale Pediatrico Microcitemico "A. Cao", Cagliari, Italy.
• ⁸ Laboratory of Virology, IRCCS, INMI L. Spallanzani, IRCCS, Rome, Italy.
• ⁹ Campus of Hematology Franco and Piera Cutino, AOOR Villa Sofia-V. Cervello, Palermo, Italy.
• ¹⁰ Department of Medicine, University of Verona & AOUI Verona, Verona, Italy.
• ¹¹ Catholic University of the Sacred Heart, Rome, Italy.