Intravenous plus intravitreal erythropoietin for management of methanol toxicity optic neuropathy: A case report and brief review

Mehran Rashidi Alavijeh; Sadegh Mazaheri-Tehrani; Amir Sepehr Saffari; Mohammadreza Fazel; Farhad Fazel

doi:10.1002/ccr3.7011

Intravenous plus intravitreal erythropoietin for management of methanol toxicity optic neuropathy: A case report and brief review

Clin Case Rep. 2023 Mar 2;11(3):e7011. doi: 10.1002/ccr3.7011. eCollection 2023 Mar.

Authors

Mehran Rashidi Alavijeh¹, Sadegh Mazaheri-Tehrani¹, Amir Sepehr Saffari¹, Mohammadreza Fazel², Farhad Fazel²

Affiliations

¹ Student Research Committee, School of Medicine Isfahan University of Medical Sciences Isfahan Iran.
² Isfahan Eye Research Center, Department of Ophthalmology Isfahan University of Medical Sciences Isfahan Iran.

Abstract

Methanol can inhibit cellular aerobic respiration pathway and causes cell hypoxia specially in optic neurons. Despite using many drugs, methanol-induced optic neuropathy (MION) still has a poor prognosis. Here we present a case of MION which is managed by a combination of intravenous and intravitreal erythropoietin in addition to corticosteroids.

Keywords: erythropoietin; methanol; optic neuropathy; toxicity.

Publication types

Case Reports