Thrombocytosis as a paraneoplastic syndrome in metastatic malignant peritoneal mesothelioma of biphasic morphology mimicking ovarian adenocarcinoma: A case report

Moustafa S Alhamadh; Rakan B Alanazi; Osama Mohaamad Wadaan; Abdulrahman Yousef Alhabeeb; Mohammad Alkaiyat; Ohoud Zaid Aljarbou; Fouad Sabatin

doi:10.1002/ccr3.6974

Thrombocytosis as a paraneoplastic syndrome in metastatic malignant peritoneal mesothelioma of biphasic morphology mimicking ovarian adenocarcinoma: A case report

Clin Case Rep. 2023 Mar 2;11(3):e6974. doi: 10.1002/ccr3.6974. eCollection 2023 Mar.

Authors

Moustafa S Alhamadh^{1

2}, Rakan B Alanazi^{1

2}, Osama Mohaamad Wadaan^{1

2}, Abdulrahman Yousef Alhabeeb^{1

2}, Mohammad Alkaiyat^{2

3}, Ohoud Zaid Aljarbou^{1

2

4}, Fouad Sabatin^{2

3}

Affiliations

¹ College of Medicine King Saud bin Abdulaziz University for Health Sciences, Ministry of the National Guard-Health Affairs Riyadh Saudi Arabia.
² King Abdullah International Medical Research Center Ministry of the National Guard-Health Affairs Riyadh Saudi Arabia.
³ Department of Medical Oncology, King Abdulaziz Medical City Ministry of the National Guard-Health Affairs Riyadh Saudi Arabia.
⁴ Department of Pathology, King Abdulaziz Medical City Ministry of the National Guard-Health Affairs Riyadh Saudi Arabia.

Abstract

Malignant peritoneal mesothelioma (MPM) is a rare malignancy, presenting with non-specific and potentially-misleading manifestations. It represents a diagnostic pitfall as it mimics ovarian carcinoma. Maintaining a low diagnostic threshold, obtaining a detailed history, and utilizing immunohistochemical markers to diagnose MPM is crucial as early diagnosis and treatment might improve survival.

Keywords: malignant mesothelioma; medical oncology; metachronous malignancy; multiple primary malignancies; peritoneal mesothelioma.

Publication types

Case Reports