Captagone & Morbid Jealousy

Psychopharmacol Bull. 2023 Feb 28;53(1):39-45.


This study aimed to explore the relationship between Captagon usage and the development of delusions of infidelity. The study sample; 101 male patients, was recruited from patients admitted to Eradah Complex for Mental Health and addiction, Jeddah, Saudi Arabia, with the diagnosis of amphetamine (Captagon) induced psychosis during the period from September 2021 to March 2022. All patients underwent an extensive psychiatric interview; including interview with patients' families; a demographic sheet, a drug use questionnaire, the structured clinical interview for DSM-IV (SCID 1), routine medical investigation, and urine screening for drugs. Patients' ages ranged from 19 to 46 years old with Mean ± SD 30.87 ± 6.58. 57.4 % were single, 77.2% have finished their high school, and 22.8% had no work. Captagon using age ranged from 14-40 years old, and regular daily dose ranged from 1-15 tablet, while maximum daily dose ranged from 2-25 tablets. Twenty-six patients (25.7%) of the study group have developed infidelity delusions. A higher divorce rate was present among patients who developed infidelity delusions (53.8%) in comparison to patients who developed other types of delusions (6.7%). Infidelity delusions are common among patients diagnosed with Captagon induce psychosis, and they harmfully influence their social lives.

Keywords: Captagon; infidelity delusions; morbid jealousy; psychosis.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Amphetamine
  • Humans
  • Jealousy*
  • Male
  • Middle Aged
  • Psychotic Disorders*
  • Schizophrenia, Paranoid
  • Young Adult


  • fenethylline
  • Amphetamine