Evaluation of Proteinuria and Hematuria in Ambulatory Setting

Pediatr Clin North Am. 2022 Dec;69(6):1037-1049. doi: 10.1016/j.pcl.2022.07.002. Epub 2022 Oct 29.

Abstract

Proteinuria and/or hematuria are common findings in ambulatory settings. Proteinuria can be glomerular and/or tubular in origin and it may be transient, orthostatic, or persistent. Persistent proteinuria may be indicative of a serious kidney pathology. Hematuria, which denotes the presence of an increased number of red blood cells in the urine, can be gross or microscopic. Hematuria can originate from the glomeruli or other sites of the urinary tract. Asymptomatic microscopic hematuria or mild proteinuria in an otherwise healthy child is less likely to be of clinical significance. However, the presence of both requires further workup and careful monitoring.

Keywords: Albuminuria; Familial hematuria; Hematuria; Microscopic hematuria; Orthostatic proteinuria; Persistent proteinuria; Proteinuria; Transient proteinuria.

Publication types

  • Review

MeSH terms

  • Ambulatory Care* / methods
  • Child
  • Hematuria* / diagnosis
  • Hematuria* / etiology
  • Humans
  • Proteinuria* / diagnosis
  • Proteinuria* / etiology