A Practical Guide to Antifungal Susceptibility Testing

J Pediatric Infect Dis Soc. 2023 Apr 28;12(4):214-221. doi: 10.1093/jpids/piad014.

Abstract

We review antifungal susceptibility testing and the development of clinical breakpoints, and detail an approach to using antifungal susceptibility results when breakpoints have not been defined. This information may prove helpful when selecting therapy for invasive fungal infections in children.

Keywords: broth microdilution; clinical breakpoint; epidemiological cutoff value; invasive fungal disease; minimum inhibitory concentration.

MeSH terms

  • Antifungal Agents* / pharmacology
  • Antifungal Agents* / therapeutic use
  • Candida
  • Fluconazole*
  • Humans
  • Microbial Sensitivity Tests

Substances

  • Antifungal Agents
  • Fluconazole