Effect of extradural morphine on somatosensory evoked potentials to dermatomal stimulation

C Lund; P Selmar; O B Hansen; C M Jensen; H Kehlet

doi:10.1093/bja/59.11.1408

Effect of extradural morphine on somatosensory evoked potentials to dermatomal stimulation

Br J Anaesth. 1987 Nov;59(11):1408-11. doi: 10.1093/bja/59.11.1408.

Authors

C Lund¹, P Selmar, O B Hansen, C M Jensen, H Kehlet

Affiliation

¹ Department of Anaesthesiology, Hvidovre University Hospital, Denmark.

PMID: 3689615
DOI: 10.1093/bja/59.11.1408

Abstract

The effect of the extradural (L2-3) administration of morphine 6 mg on early (less than 0.5 s) somatosensory evoked cortical potentials (SEP) to electrical stimulation of the L1- and S1-dermatomes was examined in eight patients. Extradural morphine did not influence SEP amplitude. SEP latency did not change, except for a minor increase in the latencies of the onset and the P2 components following S1 stimulation.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Anesthesia, Epidural
Electric Stimulation
Evoked Potentials, Somatosensory / drug effects*
Female
Humans
Male
Morphine / pharmacology*
Spinal Cord / physiology*
Time Factors

Substances

Morphine