Colonoscopy is the golden standard when screening for colorectal cancer, but the colonoscopy quality and the adenoma detection rate (ADR) vary widely among different endoscopists. Artificial intelligence (AI) can reduce performance variability by compensating for perceptual errors. As referred to in this review, several studies have shown that AI-assisted colonoscopy increases ADR significantly. AI will probably contribute to a more accurate diagnosis of patients in the future, but additional large multicenter studies are needed to assess the AI systems' actual clinical value.