Risk of malignant lymphoma in Swedish pesticide appliers

Br J Cancer. 1987 Oct;56(4):505-8. doi: 10.1038/bjc.1987.234.


The risk of Hodgkin's disease (HD) and non-Hodgkin lymphoma (NHL) was studied in a cohort of 20,245 Swedish pesticide appliers, who had the licence issued between 1965 and 1976. In this cohort 72% were estimated to have been exposed to phenoxy acid herbicides. The cohort was followed-up in the Swedish Cancer Register from date of licence until Dec. 31, 1982 or until death if prior to that date. The mean follow-up time was 12.2 years. A total of 11 cases with HD and 21 cases with NHL were observed compared to 9.1 and 20.8 expected. The relative risks and the 95% confidence intervals were for HD 1.20 (0.60-2.16) and for NHL 1.01 (0.63-1.54). The relative risk rose, but not to statistical significance however, with increased time since licence for both diagnoses.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Agricultural Workers' Diseases / chemically induced*
  • Female
  • Herbicides / adverse effects*
  • Hodgkin Disease / chemically induced*
  • Humans
  • Lymphoma, Non-Hodgkin / chemically induced*
  • Male
  • Protective Clothing
  • Risk Factors
  • Sweden


  • Herbicides