Automated Monkeypox Skin Lesion Detection Using Deep Learning and Transfer Learning Techniques

Int J Environ Res Public Health. 2023 Mar 1;20(5):4422. doi: 10.3390/ijerph20054422.


The current outbreak of monkeypox (mpox) has become a major public health concern because of the quick spread of this disease across multiple countries. Early detection and diagnosis of mpox is crucial for effective treatment and management. Considering this, the purpose of this research was to detect and validate the best performing model for detecting mpox using deep learning approaches and classification models. To achieve this goal, we evaluated the performance of five common pretrained deep learning models (VGG19, VGG16, ResNet50, MobileNetV2, and EfficientNetB3) and compared their accuracy levels when detecting mpox. The performance of the models was assessed with metrics (i.e., the accuracy, recall, precision, and F1-score). Our experimental results demonstrate that the MobileNetV2 model had the best classification performance with an accuracy level of 98.16%, a recall of 0.96, a precision of 0.99, and an F1-score of 0.98. Additionally, validation of the model with different datasets showed that the highest accuracy of 0.94% was achieved using the MobileNetV2 model. Our findings indicate that the MobileNetV2 method outperforms previous models described in the literature in mpox image classification. These results are promising, as they show that machine learning techniques could be used for the early detection of mpox. Our algorithm was able to achieve a high level of accuracy in classifying mpox in both the training and test sets, making it a potentially valuable tool for quick and accurate diagnosis in clinical settings.

Keywords: classification; deep learning; early diagnosis; image analysis; image processing; mpox.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms
  • Deep Learning*
  • Humans
  • Machine Learning
  • Mpox (monkeypox)*
  • Skin Diseases*

Grants and funding

This research was funded by the Deanship of Scientific Research, King Khalid University, Kingdom of Saudi Arabia, under grant number RGP.1/382/43.