Lung Imaging in COPD Part 2: Emerging Concepts

Chest. 2023 Aug;164(2):339-354. doi: 10.1016/j.chest.2023.02.049. Epub 2023 Mar 11.


The diagnosis, prognostication, and differentiation of phenotypes of COPD can be facilitated by CT scan imaging of the chest. CT scan imaging of the chest is a prerequisite for lung volume reduction surgery and lung transplantation. Quantitative analysis can be used to evaluate extent of disease progression. Evolving imaging techniques include micro-CT scan, ultra-high-resolution and photon-counting CT scan imaging, and MRI. Potential advantages of these newer techniques include improved resolution, prediction of reversibility, and obviation of radiation exposure. This article discusses important emerging techniques in imaging patients with COPD. The clinical usefulness of these emerging techniques as they stand today are tabulated for the benefit of the practicing pulmonologist.

Keywords: COPD; CT scan of chest; biomarkers; chest CT scan; imaging; quantitative analysis.

Publication types

  • Review
  • Research Support, N.I.H., Extramural
  • Comment

MeSH terms

  • Humans
  • Lung* / diagnostic imaging
  • Magnetic Resonance Imaging
  • Pneumonectomy
  • Pulmonary Disease, Chronic Obstructive* / diagnostic imaging
  • Tomography, X-Ray Computed