Clinical Complications and Their Management

Hematol Oncol Clin North Am. 2023 Apr;37(2):365-378. doi: 10.1016/j.hoc.2022.12.007.


The diversity of disease-related complications among patients with β-thalassemia is complicated by the wide spectrum of genotypes and clinical risk factors. The authors herein present the different complications seen in patients with β-thalassemia, the pathophysiology underlying these complications and their management.

Keywords: Complications; Endocrine; Heart; Ineffective erythropoiesis; Iron overload; Liver; Management; β-Thalassemia.

Publication types

  • Review

MeSH terms

  • Erythropoiesis
  • Humans
  • Iron Overload*
  • Risk Factors
  • beta-Thalassemia* / genetics