Mild Encephalitis/Encephalopathy with a Reversible Lesion in The Splenium

Zerrin Yıldırım; Sibel Mumcu Timer; Didem Çelik; Fazilet Karademir; Nilüfer Kale

doi:10.29399/npa.27961

Mild Encephalitis/Encephalopathy with a Reversible Lesion in The Splenium

Noro Psikiyatr Ars. 2023 Feb 18;60(1):90-96. doi: 10.29399/npa.27961. eCollection 2023.

Authors

Zerrin Yıldırım^{1

2}, Sibel Mumcu Timer³, Didem Çelik⁴, Fazilet Karademir², Nilüfer Kale²

Affiliations

¹ İstanbul University, Aziz Sancar Institute of Experimental Medicine, Department of Neuroscience, İstanbul, Turkey.
² Bağcılar Training and Research Hospital, Department of Neurology, İstanbul, Turkey.
³ Kandıra State Hospital, Department of Neurology, Kocaeli, Turkey.
⁴ Sancaktepe Şehit Prof. Dr. İlhan Varank Training and Research Hospital, Department of Neurology, İstanbul, Turkey.

Abstract

Mild encephalitis/encephalopathy with a reversible lesion in the splenium (MERS) is a clinico-radiological syndrome with mild central nervous system symptoms and a reversible lesion in the splenium of the corpus callosum. It is mainly associated with a number of viral and bacterial infections, including Coronavirus disease 2019 (COVID-19). In this paper, we report four MERS patients. One had a mumps infection, the second had aseptic meningitis, the third had Marchiafava-Bignami disease, and the fourth had atypical pneumonia associated with COVID-19 infection.

Keywords: Abducens nerve palsy; COVID-19; Marchiafava-Bignami disease; intracranial hypertension; mild encephalitis/encephalopathy with a reversible splenial lesion; mumps; papilledema.

Publication types

Case Reports