Panton-Valentine Leukocidin-Positive CC398 MRSA in Urban Clinical Settings, the Netherlands

Emerg Infect Dis. 2023 May;29(5):1055-1057. doi: 10.3201/eid2905.221717. Epub 2023 Mar 13.

Abstract

We report detection of Panton-Valentine leukocidin-positive clonal complex 398 human-origin methicillin-resistant Staphylococcus aureus L2 in the Netherlands. This hypervirulent lineage originated in the Asia-Pacific Region and could become community-acquired in Europe after recurrent travel-related introductions. Genomic surveillance enables early detection to guide control measures and help limit spread of pathogens in urban settings.

Keywords: MRSA and other staphylococci; Panton-Valentine leukocidin; Staphylococcus aureus; antimicrobial resistance; bacteria; healthcare-associated infections; the Netherlands.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Toxins
  • Community-Acquired Infections* / epidemiology
  • Exotoxins / genetics
  • Humans
  • Leukocidins / genetics
  • Methicillin-Resistant Staphylococcus aureus* / genetics
  • Netherlands / epidemiology
  • Staphylococcal Infections* / epidemiology
  • Travel
  • Travel-Related Illness

Substances

  • Exotoxins
  • Leukocidins
  • Panton-Valentine leukocidin
  • Bacterial Toxins