Bone Marrow Transplantation as a Rare Cause of Pulmonary Arterial Hypertension

Turk Kardiyol Dern Ars. 2023 Mar;51(2):151-154. doi: 10.5543/tkda.2023.13944.


The development of pulmonary arterial hypertension after bone marrow transplantation (BMT) is a rare but serious complication. In this case report, we presented the development of pulmonary arterial hypertension in a 22-year-old woman who underwent BMT due to aplastic anemia. Her symptoms on admission included shortness of breath, palpitations and fatigue. Pulmonary hypertension was classified with right heart catheterization as pul monary arterial hypertension. The patient's laboratory, echocardiographic and hemodynamic findings improved with pulmonary arterial hypertension-specific treatment. Pul monary arterial hypertension should be considered in the differ ential diagnosis of BMT patients with 'unexplained' hypoxemia or respiratory distress.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anemia, Aplastic* / complications
  • Anemia, Aplastic* / therapy
  • Bone Marrow Transplantation / adverse effects
  • Echocardiography
  • Female
  • Humans
  • Hypertension, Pulmonary* / complications
  • Pulmonary Arterial Hypertension*
  • Young Adult