Incidence and Prognosis of COVID-19 in Patients with Psoriasis: A Multicenter Prospective Study from the Eastern Black Sea Region of Turkey

Acta Dermatovenerol Croat. 2022 Dec;30(4):209-215.

Abstract

COVID-19 infection can have a poor prognosis, especially in patients with chronic diseases and those receiving immunosuppressive or immunomodulating therapies. This study aimed to investigate the severity of COVID-19 infection in patients with psoriasis and compare the infection severity for systemic treatments and comorbidities. We conducted a study in the dermatology clinics of five different centers in the Eastern Black Sea region of Turkey. Four hundred and eighty-eight patients were included, and 22.5% were confirmed as having COVID-19 infection. In our study, the frequency of hospitalization rates due to COVID-19 infection were similar (15.4%, 25.9% respectively) in patients receiving biological treatment and receiving non-biological systemic treatment (P=0.344). Hospitalization rates were higher in patients with hypertension, androgenetic alopecia, and acitretin use (P=0.043, P=0.028, P=0.040). In conclusion, current biologic treatments and non-biologic systemic treatments in patients with psoriasis did not appear to increase the risk of the severe form of COVID-19, except for acitretin.

Publication types

  • Multicenter Study

MeSH terms

  • Acitretin / adverse effects
  • Acitretin / therapeutic use
  • Black Sea
  • COVID-19* / complications
  • COVID-19* / epidemiology
  • Hospitalization / statistics & numerical data
  • Humans
  • Incidence
  • Prognosis
  • Prospective Studies
  • Psoriasis* / complications
  • Psoriasis* / epidemiology
  • Psoriasis* / therapy
  • Turkey / epidemiology

Substances

  • Acitretin