Optical Coherence Tomography-Guided Percutaneous Coronary Intervention: Evidence and Clinical Trials

Interv Cardiol Clin. 2023 Apr;12(2):225-236. doi: 10.1016/j.iccl.2022.12.004. Epub 2023 Jan 31.

Abstract

Intracoronary imaging is beneficial to optimize stent implantation and reduce the risk of stent-related complications. Optical coherence tomography (OCT) is an intravascular imaging modality that allows for detailed microstructural evaluation during the percutaneous coronary intervention (PCI). Recently, several large-scale registries, randomized trials, and meta-analyses have shown the superiority of OCT to angiography and noninferiority to IVUS with respect to both acute procedural results and mid-term clinical outcomes. This article summarizes the data supporting the application of OCT-guided PCI to several specific situations, introduces important evidence, and discusses the ongoing controversies and limitations of the current evidence base in the field of OCT-guided PCI.

Keywords: Coronary intervention; Intravascular ultrasound; Optical coherence tomography; PCI.

Publication types

  • Review

MeSH terms

  • Coronary Angiography / methods
  • Coronary Artery Disease* / surgery
  • Drug-Eluting Stents*
  • Humans
  • Percutaneous Coronary Intervention* / methods
  • Tomography, Optical Coherence / methods
  • Treatment Outcome
  • Ultrasonography, Interventional / methods