Biomechanical properties and clinical significance of cancellous bone in proximal femur: A review

Haicheng Wang; Yifan Zhang; Chuan Ren; Kai Ding; Qi Zhang; Yanbin Zhu; Wei Chen

doi:10.1016/j.injury.2023.03.010

Biomechanical properties and clinical significance of cancellous bone in proximal femur: A review

Injury. 2023 Mar 10:S0020-1383(23)00251-6. doi: 10.1016/j.injury.2023.03.010. Online ahead of print.

Authors

Haicheng Wang¹, Yifan Zhang², Chuan Ren³, Kai Ding⁴, Qi Zhang⁵, Yanbin Zhu⁶, Wei Chen⁷

Affiliations

¹ Department of orthopaedic surgery, the 3rd Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, P. R. China; Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China; Orthopaedic Institution of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China. Electronic address: 1569647282@qq.com.
² Department of orthopaedic surgery, the 3rd Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, P. R. China; Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China; Orthopaedic Institution of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China. Electronic address: 15176139858@163.com.
³ Department of orthopaedic surgery, the 3rd Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, P. R. China; Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China; Orthopaedic Institution of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China. Electronic address: 2089950551@qq.com.
⁴ Department of orthopaedic surgery, the 3rd Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, P. R. China; Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China; Orthopaedic Institution of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China. Electronic address: 2805279748@qq.com.
⁵ Department of orthopaedic surgery, the 3rd Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, P. R. China; Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China; Orthopaedic Institution of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China. Electronic address: drzhangqi1@163.com.
⁶ Department of orthopaedic surgery, the 3rd Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, P. R. China; Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China; Orthopaedic Institution of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China. Electronic address: zhuyanbin111@126.com.
⁷ Department of orthopaedic surgery, the 3rd Hospital of Hebei Medical University, Shijiazhuang 050051, Hebei, P. R. China; Key Laboratory of Biomechanics of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China; Orthopaedic Institution of Hebei Province, Shijiazhuang 050051, Hebei, P. R. China; NHC Key Laboratory of Intelligent Orthopeadic Equipment (The Third Hospital of Hebei Medical University). Electronic address: drchenwei1@163.com.

PMID: 36922271
DOI: 10.1016/j.injury.2023.03.010

Abstract

Trabecular bone plays an important role in the load-bearing capacity of the femur. Understanding the structural characteristics, biomechanics, and mechanical conduction of the trabecular bone is of great value in studying the mechanism of fractures and formulating surgical plans. The past decade has witnessed unprecedented progress in imaging, biomechanics and finite element analysis techniques, translating into a better understanding of trabecular bone. This article reviews the research progress achieved over the years regarding femoral trabecular bone, especially on factors influencing the strength of the proximal femoral cancellous bone and cancellous bone microfractures and provides a comprehensive overview of the latest findings on proximal femoral trabecular bone and their clinical significance.

Keywords: Anisotropy; BV/TV; Bone mineral density; Bone tissue modulus; Micro cracks; Proximal femur.

Publication types

Review