A novel network approach to multiscale biological regulation

Guido Gigante; Alessandro Giuliani; Maurizio Mattia

doi:10.1016/j.cels.2023.02.004

A novel network approach to multiscale biological regulation

Cell Syst. 2023 Mar 15;14(3):177-179. doi: 10.1016/j.cels.2023.02.004.

Authors

Guido Gigante¹, Alessandro Giuliani², Maurizio Mattia¹

Affiliations

¹ National Center for Radiation Protection and Computational Physics, Istituto Superiore di Sanità, 00161 Rome, Italy.
² Environment and Health Department, Istituto Superiore di Sanità, 00161 Rome, Italy. Electronic address: alessandro.giuliani@iss.it.

PMID: 36924765
DOI: 10.1016/j.cels.2023.02.004

Abstract

Modeling systems at multiple interacting scales is probably the most relevant task for pursuing a physically motivated explanation of biological regulation. In a new study, Smart and Zilman develop a convincing, albeit preliminary, model of the interplay between the cell microscale and the macroscopic tissue organization in biological systems.

MeSH terms

Models, Biological*