Advances in epigenetic modification affecting anthocyanin synthesis

Yi Chuan. 2022 Dec 20;44(12):1117-1127. doi: 10.16288/j.yczz.22-171.


Anthocyanins are a class of important flavonoid compounds widely present in plants, and play important roles in plant growth, metabolism and stress responses. In the process of growth and development, anthocyanin renders the flowers and fruits of plants displaying rich colors, attracts insect pollination and animal feeding, thereby facilitating seed spreading and dissemination. In metabolic stress, anthocyanin can resist low temperature, drought, fungal infection, ultraviolet damage, insect pests and other stress-resistant processes. The anthocyanin biosynthesis is co-regulated by related structural genes as well as transcription factor genes. Recent studies have showed that the anthocyanin biosynthesis-related genes in plants are epigenetically regulated, thus affecting the synthesis of anthocyanin glycosides. Epigenetics is one of the hot topics in the field of biological sciences. In this review, we summarize the advances of epigenetic modifications in anthocyanin biosynthesis and the application of genome editing in epigenetics, thereby providing new ideas for flower color breeding improvement by epigenetic regulation.


Keywords: CRISPR/dCas9; anthocyanin; epigenetic modifications.

Publication types

  • Review

MeSH terms

  • Anthocyanins* / genetics
  • Anthocyanins* / metabolism
  • Epigenesis, Genetic*
  • Plant Breeding
  • Plants / metabolism


  • Anthocyanins