Vinpocetine effects on cognitive impairments produced by flunitrazepam

Int Clin Psychopharmacol. 1987 Oct;2(4):325-31. doi: 10.1097/00004850-198710000-00005.

Abstract

The effects of pre-treatment with vinpocetine 40 mg, on flunitrazepam-induced impairment of memory, were studied in 8 normal volunteers. Tests of Critical Flicker Fusion Threshold, a Sternberg Memory Scanning Task, along with subjective ratings of drug action were used. Drug effects were found to be modest. Treatment with vinpocetine was associated with improvements in short-term memory processes.

Publication types

  • Clinical Trial
  • Randomized Controlled Trial

MeSH terms

  • Adult
  • Female
  • Flicker Fusion / drug effects
  • Flunitrazepam* / pharmacology
  • Humans
  • Memory / drug effects
  • Memory Disorders / chemically induced
  • Memory Disorders / prevention & control*
  • Sleep / drug effects
  • Vinca Alkaloids / pharmacology
  • Vinca Alkaloids / therapeutic use*

Substances

  • Vinca Alkaloids
  • vinpocetine
  • Flunitrazepam