Burden of disease of chronic pain in Ecuador

Expert Rev Pharmacoecon Outcomes Res. 2023 Jun;23(5):547-554. doi: 10.1080/14737167.2023.2193689. Epub 2023 Mar 29.

Abstract

Objectives: To estimate the burden of disease related to chronic pain in Ecuador.

Methods: We used Global Burden of Disease (GBD) methods to estimated disability-adjusted life years (DALYs) related to chronic pain in Ecuador related to lumbar pain, osteoarthritis, post-herpetic neuralgia, diabetic neuropathy, cancer-related pain, and other musculoskeletal pain. We estimated the prevalent cases by sex and age group using literature data. We only estimated years lived with disability using disability weights obtained from the GBD, with the assumption that no premature death would be related to pain. We used a prevalence-based approach to estimate cases by sex and age group using literature, without discounting or age adjustment. We calculated total DALYs and DALYs/100,000 inhabitants.

Results: Our estimated yielded a total of 3,644,108 patients with chronic pain. They would produce 256,090 DALYs or 1,483 DALYs/100,000 inhabitants attributable to chronic pain. Low back pain, osteoarthritis and cancer-related pain were the drivers of DALY production.

Conclusions: Chronic pain is an important source of burden of disease. It is comparable to other important causes such as headaches, stroke, diabetes and chronic obstructive pulmonary disease, among others. Low back pain, osteoarthritis and other musculoskeletal pain were the biggest contributors given their high prevalence.

Keywords: Burden of disease; Ecuador; chronic pain; disability-adjusted life years; pain.

MeSH terms

  • Cancer Pain*
  • Chronic Pain* / epidemiology
  • Chronic Pain* / etiology
  • Ecuador / epidemiology
  • Global Burden of Disease
  • Global Health
  • Humans
  • Life Expectancy
  • Low Back Pain*
  • Musculoskeletal Pain*
  • Quality-Adjusted Life Years
  • Risk Factors