A case-control study of drinking beverages and the risk of multiple sclerosis in Iran

J Health Popul Nutr. 2023 Mar 23;42(1):22. doi: 10.1186/s41043-023-00364-8.

Abstract

Background: There is no study in the world on the relationship between consuming black and green tea as beverages containing polyphenols and the risk of MS. This study aimed to determine the association between the consumption of green and black tea, coffee, non-alcoholic beer, milk, fruit juices and carbonated beverages with the risk of MS.

Methods and materials: This case-control study was performed on 150 patients with MS and 300 healthy individuals as a control group among patients who were referred to the ophthalmology ward of a referral hospital in Ahvaz with the groups matching for age. The data collection tool was a researcher-made questionnaire including demographic information and beverage consumption. Analysis was performed using univariate and multiple logistic regression models.

Results: The mean age of patients at the time of diagnosis was 38.55 ± 8.88 years. The results showed that drinking milk (OR = 5.46), natural juice (OR = 2.49), and carbonated beverages (OR = 16.17) were associated with an increased chance of developing MS. However, drinking non-alcoholic beer (OR = 0.48), black tea (OR = 0.20), green tea (OR = 0.29) and coffee (OR = 0.07) were associated with a reduced chance of developing MS.

Conclusion: The results show that drinking black and green tea, non-alcoholic beer, and coffee are associated with a decrease in the chance of developing MS. The results of this study can be used to design interventional research and to change people's lifestyles to prevent MS.

Keywords: Beverages; Black tea; Carbonated beverages; Coffee; Green tea; Multiple sclerosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Animals
  • Beverages / adverse effects
  • Case-Control Studies
  • Coffee* / adverse effects
  • Humans
  • Iran / epidemiology
  • Middle Aged
  • Milk
  • Multiple Sclerosis* / epidemiology
  • Multiple Sclerosis* / etiology
  • Tea / adverse effects

Substances

  • Coffee
  • Tea