Evaluation of a therapeutic carbon beam using a G2000 glass scintillator

Akihito Yokoyama; Wataru Kada; Makoto Sakai; Kenta Miura; Osamu Hanaizumi

doi:10.1016/j.apradiso.2023.110753

Evaluation of a therapeutic carbon beam using a G2000 glass scintillator

Appl Radiat Isot. 2023 Jun:196:110753. doi: 10.1016/j.apradiso.2023.110753. Epub 2023 Feb 27.

Authors

Akihito Yokoyama¹, Wataru Kada², Makoto Sakai³, Kenta Miura², Osamu Hanaizumi²

Affiliations

¹ Department of Advanced Photon Research, Kansai Photon Science Institute, National Institutes for Quantum Science and Technology (QST), 8-1-7 Umemidai, Kizugawa, Kyoto, 619-0215, Japan. Electronic address: yokoyama.akihito@qst.go.jp.
² Graduate School of Science and Technology, Gunma University, 1-5-1 Tenjin-cho, Kiryu, Gunma, 376-8515, Japan.
³ Heavy Ion Medical Center, Gunma University, 3-39-22 Showa-Machi, Maebashi, Gunma, 371-8511, Japan.

PMID: 36966616
DOI: 10.1016/j.apradiso.2023.110753

Abstract

A G2000 glass scintillator (G2000-SC) was used to determine the carbon profile and range of a 290-MeV/n carbon beam used in heavy-ion therapy because it was sensitive enough to detect single-ion hits at hundreds of mega electron Volts. An electron-multiplying charge-coupled device camera was used to detect the ion luminescence generated during the irradiation of G2000-SC with the beam. The resulting image showed that the position of the Bragg peak can be determined. The beam passes through the 112-mm-thick water phantom and stops 5.73 ± 0.03 mm from the incident side to the G2000-SC. Additionally, the location of the Bragg peak was simulated when irradiating G2000-SC with the beam using the Monte Carlo code particle and heavy ion transport system (PHITS). Simulation results show that the incident beam stops at 5.60 mm after entering G2000-SC. The beam stop location obtained from images and the PHITS code is defined at 80% distal fall-off from the Bragg peak position. Consequently, G2000-SC provided effective profile measurements of therapeutic carbon beams.