Primary Pancreatic Undifferentiated Pleomorphic Sarcoma

Mehrie Harshad Patel; Daniela Guerrero Vinsard; Upasana Agrawal; Ryan W Kendziora; Brittany L Siontis; Santhi Swaroop Vege; Seth Sweetser

doi:10.14309/crj.0000000000001011

Primary Pancreatic Undifferentiated Pleomorphic Sarcoma

ACG Case Rep J. 2023 Mar 22;10(3):e01011. doi: 10.14309/crj.0000000000001011. eCollection 2023 Mar.

Authors

Mehrie Harshad Patel¹, Daniela Guerrero Vinsard², Upasana Agrawal³, Ryan W Kendziora⁴, Brittany L Siontis⁵, Santhi Swaroop Vege², Seth Sweetser²

Affiliations

¹ Department of Cardiovascular Diseases, Mayo Clinic, Rochester, MN.
² Department of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN.
³ Department of Internal Medicine, Louisiana State University, Shreveport, LA.
⁴ Department of Anatomic and Clinical Pathology, Mayo Clinic, Rochester, MN.
⁵ Department of Medical Oncology, Mayo Clinic, Rochester, MN.

Abstract

Primary pancreatic sarcomas are rare malignancies with an incidence of 0.1%. This case report is of a 48-year-old man who presented with this condition. The patient's treatment plan consisted of distal pancreatectomy and splenectomy with intraoperative immunohistochemistry and adjuvant chemotherapy. To correctly identify and treat undifferentiated pleomorphic sarcoma, a stepwise strategy involving cross-sectional imaging and extensive histopathology analysis is necessary.

Keywords: mass; pancreas; pancreatic malignancy; pancreatic mass; pancreatic neoplasm; sarcoma; undifferentiated; undifferentiated sarcoma.

Publication types

Case Reports