Objective:To investigate the etiological characteristics of nasal bacterial infection in patients with nasal lymphoma. Methods:The results of bacterial culture of nasal secretions from 39 healthy people and 86 patients with nasal lymphoma in the Affiliated Hospital of Qingdao University from January 2019 to June 2022 were retrospectively analyzed, and the differences in nasal bacteria distribution between nasal lymphoma and healthy people were analyzed and compared. Results:Corynebacterium（38.90%） was the most common bacteria in the nasal cavity of healthy people, followed by coagulase-negative Staphylococcus（31.95%）, Staphylococcus epidermidis（15.28%） and Staphylococcus aureus（6.95%）. The most common bacteria in nasal lymphoma patients was Staphylococcus aureus（30.37%）, followed by Corynebacterium（9.63%）, Staphylococcus epidermidis（7.41%） and coagulase negative Staphylococcus（6.67%）. A total of 81 nasal lymphoma patients were detected with bacteria, positive rate is as high as 94.19%（81/86）. Conclusion:Staphylococcus aureus is the main pathogenic bacteria in nasal secretion of patients with nasal lymphoma, which provides guiding significance for the clinical prevention and treatment of nasal lymphoma complicated with infection or not.
目的：探索鼻部淋巴瘤患者鼻腔分泌物中细菌的分布特点。 方法：回顾性分析青岛大学附属医院2019年1月—2022年6月就诊的86例鼻部淋巴瘤患者与39例健康体检人员总鼻道的鼻分泌物的细菌培养结果，分析和比较鼻部淋巴瘤与健康人群鼻腔细菌分布的差异。 结果：健康人群鼻部细菌以棒状杆菌最多（38.90%），其次为凝固酶阴性葡萄球菌（31.95%）、表皮葡萄球菌（15.28%）、金黄色葡萄球菌（6.95%）；而鼻部淋巴瘤患者鼻部细菌分布则以金黄色葡萄球菌最多（30.37%），其次为棒状杆菌（9.63%）、表皮葡萄球菌（7.41%）、凝固酶阴性葡萄球菌（6.67%）。其中81例患者检出细菌，阳性率高达94.19%（81/86）。 结论：鼻部淋巴瘤患者鼻分泌物中的细菌分布与健康人相比存在显著差异，其致病菌以金黄色葡萄球菌为主，这为临床上预防和治疗鼻部淋巴瘤或合并感染提供了指导意义。.
Keywords: infection; lymphoma; microbiology; staphylococcus aureus.
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