Specifications of standards in systems and synthetic biology: status and developments in 2022 and the COMBINE meeting 2022

J Integr Bioinform. 2023 Mar 29;20(1):20230004. doi: 10.1515/jib-2023-0004. eCollection 2023 Mar 1.


This special issue of the Journal of Integrative Bioinformatics contains updated specifications of COMBINE standards in systems and synthetic biology. The 2022 special issue presents three updates to the standards: CellML 2.0.1, SBML Level 3 Package: Spatial Processes, Version 1, Release 1, and Synthetic Biology Open Language (SBOL) Version 3.1.0. This document can also be used to identify the latest specifications for all COMBINE standards. In addition, this editorial provides a brief overview of the COMBINE 2022 meeting in Berlin.

Publication types

  • Editorial

MeSH terms

  • Computational Biology*
  • Programming Languages
  • Software
  • Synthetic Biology*