Effect of honey dressing in the management of diabetic foot ulcers: A meta-analysis

Int Wound J. 2023 Sep;20(7):2626-2633. doi: 10.1111/iwj.14135. Epub 2023 Mar 30.

Abstract

A meta-analysis study to assess the effect of honey dressing (HD) in the management of diabetic foot ulcer (DFU). A comprehensive literature examination till January 2023 was implemented and 1794 linked studies were appraised. The picked studies contained 882 subjects with DFUs were in the picked studies' baseline, 424 of them were using HD, and 458 were using a control. Odds ratio (OR) in addition to 95% confidence intervals (CIs) were used to calculate the consequence of HD in the management of DFUs after DFU by the dichotomous and continuous styles and a fixed or random model. The HD applied to DFUs caused a significantly higher wound healing rate (OR, 2.06; 95% CI, 1.45-2.93, P < .001) and lower wound healing time (MD, -10.42; 95% CI, -16.27- -4.58, P < .001) compared with the control. The HD applied to DFUs caused a significantly higher wound healing rate and lower wound healing time compared with the control. Although precautions should be taken when commerce with the consequences since most of the picked studies for this meta-analysis was with low sample sizes.

Keywords: diabetic foot ulcer; honey dressing; wound healing rate; wound healing time.

Publication types

  • Meta-Analysis

MeSH terms

  • Bandages, Hydrocolloid
  • Diabetes Mellitus*
  • Diabetic Foot* / diagnosis
  • Diabetic Foot* / therapy
  • Honey*
  • Humans
  • Wound Healing