A biobased magnetic dual-dummy-template molecularly imprinted polymer using a deep eutectic solvent as a coporogen for highly selective enrichment of organophosphates

Nilawan Surapong; Prachathipat Pongpinyo; Yanawath Santaladchaiyakit; Rodjana Burakham

doi:10.1016/j.foodchem.2023.136045

A biobased magnetic dual-dummy-template molecularly imprinted polymer using a deep eutectic solvent as a coporogen for highly selective enrichment of organophosphates

Food Chem. 2023 Aug 30:418:136045. doi: 10.1016/j.foodchem.2023.136045. Epub 2023 Mar 25.

Authors

Nilawan Surapong¹, Prachathipat Pongpinyo², Yanawath Santaladchaiyakit³, Rodjana Burakham⁴

Affiliations

¹ Materials Chemistry Research Center, Department of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand.
² Agricultural Production Sciences Research and Development Office, Department of Agriculture, Bangkok 10900, Thailand.
³ Department of Chemistry, Faculty of Engineering, Rajamangala University of Technology Isan, Khon Kaen Campus, Khon Kaen 40000, Thailand.
⁴ Materials Chemistry Research Center, Department of Chemistry, Faculty of Science, Khon Kaen University, Khon Kaen 40002, Thailand. Electronic address: rodjbu@kku.ac.th.

PMID: 36996646
DOI: 10.1016/j.foodchem.2023.136045

Abstract

An eco-friendly magnetic dual-dummy-template molecularly imprinted polymer (MDDMIP) was prepared by a "one-pot" green synthesis using mixed-valence iron hydroxide as the magnetic material, a deep eutectic solvent as the coporogen, and caffeic acid and glutamic acid as binary monomers. The adsorption properties toward organophosphorus pesticides (OPPs) were investigated. High adsorption capacities (269.65-304.93 mg g^-1), quick adsorption times (20 s), and high imprinting factors (2.28-3.83) were obtained. The proposed MDDMIP was utilized for magnetic solid phase extraction (MSPE) of OPPs prior to quantification by high performance liquid chromatography (HPLC). The developed method exhibited outstanding linearity (0.05-500 μg L^-1), low detection limits (0.003-0.015 μg L^-1), and excellent enrichment factors (940-1310 folds). The MSPE-HPLC method was successfully applied for the detection of OPPs in vegetable, fruit, and grain samples with acceptable recoveries (80-119%). This method is a good potential method for the analysis of pesticide residues in complex matrices.

Keywords: Deep eutectic solvent; Dual template; Dummy template; Magnetic solid phase extraction; Molecularly imprinted polymer.

MeSH terms

Adsorption
Chromatography, High Pressure Liquid / methods
Deep Eutectic Solvents
Magnetic Phenomena
Molecular Imprinting* / methods
Molecularly Imprinted Polymers
Organophosphates
Organophosphorus Compounds
Pesticides*
Polymers / chemistry
Solid Phase Extraction / methods
Solvents / chemistry

Substances

Solvents
Molecularly Imprinted Polymers
Deep Eutectic Solvents
Organophosphates
Polymers
Organophosphorus Compounds
Pesticides