Why are whales big? Genes behind ocean giants

Trends Genet. 2023 Jun;39(6):436-438. doi: 10.1016/j.tig.2023.03.005. Epub 2023 Mar 28.

Abstract

Gigantism is prevalent in animals, but it has never reached more extreme levels than in aquatic mammals such as whales, dolphins, and porpoises. A new study by Silva et al. has uncovered five genes underlying this gigantism, a phenotype with important connections to aging and cancer suppression in long-lived animals.

Keywords: Peto’s paradox; cancer; cetaceans; gigantism; mammals; molecular evolution.

MeSH terms

  • Animals
  • Neoplasms* / genetics
  • Oceans and Seas
  • Whales* / genetics