A case report of CBD and THC as analgesic therapy in a cat with chronic osteoarthritic pain

Vet Med Sci. 2023 May;9(3):1021-1025. doi: 10.1002/vms3.1057. Epub 2023 Mar 31.


A 10-year-old mixed breed male cat presented with clinical signs related to chronic orthopaedic pain. Upon physical examination, pain was noted, based on the feline Musculoskeletal Pain Index (FMPI). An analgesic treatment with a full spectrum cannabis oil (1.8% CBD and 0.8% THC) was proposed for 30 days (0,5 mg/kg based on CBD). The FMPI scale score decreased more than 50%. This case reported a satisfactory outcome for the patient and the owner, although this medication could increase ALT. Given the paucity of literature published to date on the treatment of veterinary species with cannabis-based medications, further clinical and pharmacokinetic studies are necessary to study the safety and efficacy of its use.

Keywords: cannabidiol; cannabis; chronic pain; osteoarthritis; tetrahydrocannabinol.

Publication types

  • Case Reports

MeSH terms

  • Analgesics / therapeutic use
  • Animals
  • Cannabidiol* / therapeutic use
  • Cats
  • Chronic Pain* / drug therapy
  • Chronic Pain* / veterinary
  • Dronabinol / therapeutic use
  • Male


  • Dronabinol
  • Cannabidiol
  • Analgesics