A global perspective of delayed cord clamping in infants

Semin Perinatol. 2023 Jun;47(4):151748. doi: 10.1016/j.semperi.2023.151748. Epub 2023 Mar 17.


Delayed umbilical cord clamping, DCC, a practice in which the umbilical cord is not clamped immediately after birth, promotes placental transfusion to preterm and term neonates. DCC may improve outcomes in preterm neonates by reducing mortality and blood transfusion requirements and increasing iron stores. Despite the recommendations from multiple governing bodies, including the World Health Organization, research on DCC in LMICs remains limited. Given that iron deficiency is prevalent, and most neonatal deaths occur in LMICs, DCC has the potential to improve outcomes in these settings. This article aims to provide a global perspective on DCC in LMICs and to identify knowledge gaps that offer future research opportunities.

Keywords: Anemia; Low-and-middle income; Neonatal; Neurodevelopment; Preterm.

MeSH terms

  • Blood Transfusion
  • Female
  • Humans
  • Infant
  • Infant, Newborn
  • Parturition
  • Placenta*
  • Pregnancy
  • Umbilical Cord
  • Umbilical Cord Clamping*