The possibility of anesthesia stimulated by a train of current pulses

Mikhail N Shneider; Mikhail Pekker

doi:10.1088/2057-1976/acca21

The possibility of anesthesia stimulated by a train of current pulses

Biomed Phys Eng Express. 2023 Apr 27;9(3). doi: 10.1088/2057-1976/acca21.

Authors

Mikhail N Shneider¹, Mikhail Pekker²

Affiliations

¹ Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ, United States of America.
² 310 Elm Road, Apt.G29, Princeton, NJ, 08540, United States of America.

PMID: 37015190
DOI: 10.1088/2057-1976/acca21

Abstract

This study considers a simple theoretical model of blocking the passage of signals (action potentials) from sensory neurons, thereby affecting anesthesia without the use of anesthetics as a result of a sequence of unipolar current pulses generated by an external source. The proposed model allows the selection of parameters and the required frequency of the repetition of current pulses for the possible implementation of anesthesia, depending on the electrical characteristics of the skin and the conductivity of the saline solution in which the myelinated nerve fibers are located.

Keywords: action potential; anesthesia; current pulses; external stimulation.

Creative Commons Attribution license.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Action Potentials / physiology
Anesthesia*
Electric Stimulation
Skin