A double-blind crossover comparison of topical anesthetics

J Am Dent Assoc. 1979 Feb;98(2):213-4. doi: 10.14219/jada.archive.1979.0476.

Abstract

Three topical anesthetics and a placebo were compared in 102 separate trials. The degree of anesthesia produced with each agent was determined by placing a needle in the palate near the palatal foramen. Pain produced was rated by the participants on a scale from 1 to 5.

Publication types

  • Clinical Trial
  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Administration, Topical
  • Adult
  • Anesthetics, Local / administration & dosage*
  • Benzocaine / administration & dosage
  • Clinical Trials as Topic
  • Double-Blind Method
  • Drug Evaluation
  • Female
  • Humans
  • Lidocaine / administration & dosage
  • Male
  • Pain / prevention & control
  • Placebos
  • Tetracaine / administration & dosage

Substances

  • Anesthetics, Local
  • Placebos
  • Tetracaine
  • Lidocaine
  • Benzocaine