Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2023 May 16;329(19):1697-1699.
doi: 10.1001/jama.2023.5348.

Risk of Death in Patients Hospitalized for COVID-19 vs Seasonal Influenza in Fall-Winter 2022-2023

Yan Xie  1 , Taeyoung Choi  1 , Ziyad Al-Aly  1
Affiliations

Risk of Death in Patients Hospitalized for COVID-19 vs Seasonal Influenza in Fall-Winter 2022-2023

Yan Xie et al. JAMA. .
No abstract available

Plain language summary

This study uses data from the US Department of Veterans Affairs to assess whether SARS-CoV-2 remains associated with higher risk of death compared with seasonal influenza in fall-winter 2022-2023.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest Disclosures: Dr Xie reported serving as a consultant (uncompensated) for Pfizer. Dr Al-Aly reported receiving consulting fees from Gilead Sciences and Tonix Pharmaceuticals and serving as a consultant (uncompensated) for Pfizer. No other disclosures were reported.

Figures

Figure.
Figure.. Hazard Ratio, Death Rates, and Percentage of Excess Deaths in COVID-19 Compared With Seasonal Influenza
Comparison conducted in overall cohort by age (≤65, >65 years) and by COVID-19 vaccination status (unvaccinated, 1-2 doses of vaccine, and boosted), SARS-CoV-2 infection status (with primary SARS-CoV-2 infection and reinfection), and outpatient COVID-19 antiviral treatment (yes or no), compared with overall seasonal influenza. Outpatient COVID-19 antiviral treatment included nirmatrelvir-ritonavir, molnupiravir, or remdesivir.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Xie Y, Bowe B, Maddukuri G, Al-Aly Z. Comparative evaluation of clinical manifestations and risk of death in patients admitted to hospital with Covid-19 and seasonal influenza: cohort study. BMJ. 2020;371:m4677. doi:10.1136/bmj.m4677 - DOI - PMC - PubMed
    1. Cates J, Lucero-Obusan C, Dahl RM, et al. . Risk for in-hospital complications associated with COVID-19 and influenza—Veterans Health Administration, United States, October 1, 2018–May 31, 2020. MMWR Morb Mortal Wkly Rep. 2020;69(42):1528-1534. doi:10.15585/mmwr.mm6942e3 - DOI - PMC - PubMed
    1. Laboratory-confirmed COVID-19–associated hospitalizations. Centers for Disease Control and Prevention . Accessed March 7, 2023. https://gis.cdc.gov/grasp/covidnet/covid19_3.html
    1. Influenza Hospitalization Surveillance Network (FluSurv-NET). Accessed March 7, 2023. Centers for Disease Control and Prevention . https://www.cdc.gov/flu/weekly/influenza-hospitalization-surveillance.htm
    1. Portmann L, de Kraker MEA, Fröhlich G, et al. ; CH-SUR Study Group . Hospital outcomes of community-acquired SARS-CoV-2 Omicron variant infection compared with influenza infection in Switzerland. JAMA Netw Open. 2023;6(2):e2255599-e99. doi:10.1001/jamanetworkopen.2022.55599 - DOI - PMC - PubMed

Publication types