Chemical reprogramming takes the fast lane

Cell Stem Cell. 2023 Apr 6;30(4):335-337. doi: 10.1016/j.stem.2023.03.001.


Small molecule-induced cell fate transitions are characterized by low efficiency and slow kinetics. An optimized chemical reprogramming approach now facilitates the robust and rapid conversion of somatic cells to pluripotent stem cells, unlocking exciting avenues to study and manipulate human cell identity.

Publication types

  • Comment

MeSH terms

  • Cell Differentiation
  • Cellular Reprogramming
  • Humans
  • Induced Pluripotent Stem Cells*
  • Pluripotent Stem Cells*