Surgical Treatment of Early Glottic Cancer

Otolaryngol Clin North Am. 2023 Apr;56(2):259-273. doi: 10.1016/j.otc.2022.12.009.


The incidence of all head and neck malignancies is rising worldwide, with carcinoma of the larynx constituting approximately 1% of all cancers. Early glottic cancer responds quite favorably to surgical intervention due to its early presentation, coupled with the low rate of regional and distant metastases. This article focuses on various approaches to the surgical treatment of early glottic cancer. Details include the clinical and radiological evaluation of laryngeal cancer, the goals of treatment, current surgical options for early disease, approach to surgical resection margins and management of nodal disease, and complications associated with each treatment modality.

Keywords: Early glottic cancer; Endoscopic surgery; Laryngeal cancer; Transoral laser microsurgery; Vocal fold.

Publication types

  • Review

MeSH terms

  • Carcinoma, Squamous Cell* / surgery
  • Glottis / surgery
  • Humans
  • Laryngeal Neoplasms* / pathology
  • Laryngeal Neoplasms* / surgery
  • Laser Therapy*
  • Microsurgery
  • Neoplasm Staging
  • Retrospective Studies