Surgical Management of Advanced Glottic Cancer

Seerat K Poonia; Elizabeth Nicolli

doi:10.1016/j.otc.2022.12.007

Surgical Management of Advanced Glottic Cancer

Otolaryngol Clin North Am. 2023 Apr;56(2):275-283. doi: 10.1016/j.otc.2022.12.007.

Authors

Seerat K Poonia¹, Elizabeth Nicolli²

Affiliations

¹ Department of Otolaryngology - Head and Neck Surgery, Miller School of Medicine, University of Miami Hospital, 1121 NW 14th Street, Sylvester Medical Office Building, 3rd Floor, Suite 325 Miami, FL 33136, USA.
² Department of Otolaryngology - Head and Neck Surgery, Miller School of Medicine, University of Miami Hospital, 1121 NW 14th Street, Sylvester Medical Office Building, 3rd Floor, Suite 325 Miami, FL 33136, USA. Electronic address: exn164@med.miami.edu.

PMID: 37030940
DOI: 10.1016/j.otc.2022.12.007

Abstract

In advanced glottic cancer, it is widely known that definitive chemoradiation can result in comparable survival outcomes to primary surgery. This deserves consideration given the immense effects total laryngectomy (TL) has on patients. It is important to consider that not all advanced glottic tumors should be treated in the same way, and surgical management remains a critical consideration for optimization of local control and survival outcomes. Advances in organ preservation surgery and the more developed understanding of the survival benefits of TL in extensive T4 disease further support the importance of surgery in the management of advanced glottic cancer.

Keywords: Advanced glottic cancer; Laryngectomy; Organ preservation; Primary chemoradiation.

Publication types

Review

MeSH terms

Chemoradiotherapy
Glottis / surgery
Humans
Laryngeal Neoplasms* / pathology
Laryngeal Neoplasms* / surgery
Laryngectomy
Neoplasm Staging
Retrospective Studies