Transversus abdominis plane block for anterior lumbar interbody fusion: a randomized controlled trial

Spine J. 2023 Aug;23(8):1137-1143. doi: 10.1016/j.spinee.2023.03.013. Epub 2023 Apr 7.

Abstract

Background context: Anterior lumbar interbody fusion (ALIF) is a lumbar arthrodesis technique via an anterior approach that is less invasive than the posterior approaches. However, it is associated with specific pain in the abdominal wall.

Purpose: The objective of this study was to determine whether performing a bilateral ultrasound-guided Transversus abdominis plane (TAP) block allows a reduction in morphine consumption in the first 24 hours after surgery.

Study design: This study is a prospective single-center, randomized, double-blind study.

Patient sample: Patients undergoing ALIF surgery were included and randomized into two groups. Both groups received a TAP block performed at the end of surgery with either ropivacaine or placebo.

Outcome measures: The primary outcome measure was morphine consumption in the first 24 hours. The main secondary outcomes were immediate postoperative pain and opioid-related side effects.

Methods: Intra- and postoperative anesthesia and analgesia protocols where standardized. A bilateral ultrasound-guided TAP block was performed with 75 mg (in 15 mL) of ropivacaine per side or isotonic saline serum depending on their assignment group.

Results: Forty-two patients were included in the study (21 per group). Morphine consumption at 24 hours (28 mg [18-35] in the ropivacaine group versus 25 mg [19-37] in the placebo group [p=.503]) were not significantly different between the two groups.

Conclusion: TAP block with ropivacaine or placebo provided a similar postoperative analgesia when associated with a multimodal analgesia protocol for ALIF.

Keywords: Analgesia; Anterior lumbar interbody fusion; Multimodal; Postoperative pain; Regional analgesia; Transversus abdominis plane block.

Publication types

  • Randomized Controlled Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Abdominal Muscles* / diagnostic imaging
  • Analgesics, Opioid
  • Anesthetics, Local*
  • Double-Blind Method
  • Humans
  • Morphine
  • Pain, Postoperative / etiology
  • Pain, Postoperative / prevention & control
  • Prospective Studies
  • Ropivacaine

Substances

  • Ropivacaine
  • Anesthetics, Local
  • Morphine
  • Analgesics, Opioid